Full Spectrum Oregon Grape Root

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Promote gastrointestinal health with Swanson Oregon Grape Root! Oregon grape root was a favorite of Native Americans in the northwest before European colonists arrived. Ironically, the fruit of this evergreen shrub are not grapes. Alkaloids, including berberine, berbamine, canadine, and hydrastine, may account for the activity of Oregon grape. Each capsule delivers 400 mg of Oregon grape root.


Supplement Facts

Serving Size 1 Capsule

Servings Per Container 60

Amount Per Serving % Daily Value
Oregon-Grape Root (Mahonia aquifolium) 400 mg *

*Daily Value not established.

Other Ingredients: Gelatin, rice flour, magnesium stearate.

Suggested Use: As a dietary supplement, take one capsule one to two times per day with water.

Warning: For adults only. Do not take this product if you are pregnant or nursing. Consult your healthcare provider before use if you are taking any prescription medications. Not recommended for long-term use.

Storage Instructions: Keep out of reach of children. Do not use if seal is broken. Store in a cool, dry place.




  1. Does Oregon grape naturally contain berberine?
    Yes. Oregon grape root (Berberis aquifolium) naturally contains berberine, along with related isoquinoline alkaloids such as berbamine and jatrorrhizine. These bioactive compounds have been extensively studied for their antioxidant properties and their role in supporting digestive, liver, and metabolic wellness.
  2. How does Oregon grape support digestive health?
    Oregon grape contains naturally occurring alkaloids, including berberine, that have been studied for their ability to support a healthy balance of the gut microbiome and normal digestive function. These compounds also support the integrity of the intestinal lining and help maintain digestive comfort as part of a healthy gastrointestinal system.
  3. How does Oregon grape support liver wellness?
    The berberine and other plant alkaloids found in Oregon grape have been studied for their antioxidant activity and their ability to support normal liver cell function. By helping protect cells from oxidative stress and supporting healthy metabolic processes, these compounds contribute to overall liver wellness.
  4. Why choose a full-spectrum herbal supplement?
    Full-spectrum herbal supplements use the whole herb rather than an isolated compound or highly concentrated extract. This approach preserves the herb's naturally occurring phytochemicals—including flavonoids, polyphenols, essential oils, and other plant constituents—in proportions found in nature. Many people choose full-spectrum herbs because they provide a more traditional approach to botanical supplementation, reflecting how these plants have been used for centuries.
  5. Is Swanson Full Spectrum Oregon Grape Root suitable for special diets?
    Swanson Full Spectrum Oregon Grape Root is made with non-GMO ingredients and is formulated without gluten or dairy. It is not suitable for vegan or vegetarian lifestyles because it contains a gelatin capsule, which is animal-derived. Individuals following plant-based diets should review the ingredient list before use.


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